Albumin Globulin (A/G) Ratio Calculator
Calculate the ratio of albumin to globulin proteins in your blood.
Your Calculated A/G Ratio:
Disclaimer: This calculator is for educational purposes only. Results should be interpreted by a qualified medical professional in the context of a complete clinical evaluation.
Understanding the A/G Ratio
The Albumin/Globulin (A/G) ratio is a standard part of a Comprehensive Metabolic Panel (CMP) or a liver function test. It compares the amount of albumin—a protein produced by the liver that keeps fluid from leaking out of blood vessels—to the amount of globulin, which includes enzymes, antibodies, and other proteins.
Because the laboratory usually measures "Total Protein" and "Albumin" directly, the globulin value is calculated by subtracting albumin from the total protein. The ratio is then determined by dividing the albumin value by the calculated globulin value.
The Mathematical Formula
The calculation follows two steps:
- Globulin Calculation: Total Protein – Albumin = Globulin
- Ratio Calculation: Albumin / Globulin = A/G Ratio
Normal Range Interpretation
A normal A/G ratio typically falls between 1.1 and 2.5. However, laboratory reference ranges can vary slightly.
| Result Type | Possible Causes |
|---|---|
| Low A/G Ratio | Liver disease (cirrhosis), kidney disease (nephrotic syndrome), autoimmune disorders (Lupus), or multiple myeloma. |
| High A/G Ratio | Underproduction of globulins (genetic deficiencies, some leukemias), or high-protein diets. |
| Normal A/G Ratio | Suggests a healthy balance of proteins, though individual levels should still be checked against reference ranges. |
Example Calculation
If a patient's lab results show:
- Albumin: 4.0 g/dL
- Total Protein: 7.5 g/dL
First, calculate Globulin: 7.5 – 4.0 = 3.5 g/dL.
Next, calculate the ratio: 4.0 / 3.5 = 1.14.
In this case, the ratio is within the normal range.