Estimate the risk level of Cervical Intraepithelial Neoplasia (CIN)
Negative
Positive (e.g., HPV 16 or 18)
Positive (Other HR-HPV types)
Unknown / Not Tested
Normal / NILM
ASC-US / LSIL
ASC-H / HSIL
Never Screened
Never Smoker
Former Smoker
Current Smoker
Normal
Compromised (HIV+, Organ Transplant, etc.)
Over 20
17 – 20
Under 17
1 partner
2 – 5 partners
More than 5 partners
Calculated Score:
Disclaimer: This tool is for educational purposes only. It does not provide a medical diagnosis. CIN can only be diagnosed through clinical examination, Pap tests, HPV DNA testing, and colposcopy/biopsy by a licensed healthcare professional.
Cervical Intraepithelial Neoplasia (CIN) refers to the abnormal growth of cells on the surface of the cervix. While CIN is not cancer, it is considered a precancerous condition that, if left untreated, could potentially develop into cervical cancer over several years.
The Grades of CIN
Grade
Description
Typical Management
CIN 1
Low-grade; affects 1/3 of the epithelial thickness.
Often monitored; frequently clears on its own.
CIN 2
Moderate-grade; affects 2/3 of the thickness.
May require treatment (LEEP or Laser) or close monitoring.
CIN 3
High-grade; affects full thickness; carcinoma in situ.
Surgical removal or ablation is usually required.
Critical Risk Factors Explained
Several factors increase the likelihood of developing CIN. The primary driver is the Human Papillomavirus (HPV), specifically high-risk strains like HPV 16 and 18. However, co-factors play a significant role:
HPV Infection: The presence of high-risk HPV is the most significant indicator of CIN development.
Smoking: Tobacco by-products can damage the DNA of cervical cells and weaken the immune response in cervical tissue.
Immunosuppression: A weakened immune system (due to conditions like HIV) makes it harder for the body to clear HPV infections.
Sexual History: Early exposure to HPV and multiple partners increase the cumulative risk of contracting high-risk viral strains.
Example Scenarios
Scenario A: A 30-year-old non-smoker with a negative HPV test and normal Pap history.
Result: Low Risk. Routine screening is typically recommended every 3-5 years.
Scenario B: A 35-year-old smoker who tested positive for HPV 16 and has an ASC-US Pap result.
Result: High Risk. Immediate colposcopy is often indicated to check for high-grade CIN lesions.
What to Do if You Are at High Risk?
If your risk score is elevated, it is essential to consult a gynecologist. They may recommend a Colposcopy, which allows for a magnified view of the cervix, or a Biopsy to confirm the presence and grade of CIN. Early detection through regular screening remains the most effective way to prevent cervical cancer.
function calculateCINRisk() {
var hpv = parseFloat(document.getElementById("hpvStatus").value);
var pap = parseFloat(document.getElementById("papHistory").value);
var smoke = parseFloat(document.getElementById("smokingStatus").value);
var immune = parseFloat(document.getElementById("immuneStatus").value);
var sexHist = parseFloat(document.getElementById("sexualHistory").value);
var partners = parseFloat(document.getElementById("partnersCount").value);
var totalScore = hpv + pap + smoke + immune + sexHist + partners;
var resultDiv = document.getElementById("cinResult");
var riskLevelTxt = document.getElementById("riskLevel");
var riskDescTxt = document.getElementById("riskDescription");
var scoreValTxt = document.getElementById("scoreValue");
resultDiv.style.display = "block";
scoreValTxt.innerHTML = totalScore;
if (totalScore = 25 && totalScore < 55) {
resultDiv.className = "cin-result-box risk-moderate";
riskLevelTxt.innerHTML = "Moderate Risk Profile";
riskDescTxt.innerHTML = "You have factors that may increase your risk of CIN. Ensure you follow up on any pending tests and discuss these results with a healthcare provider.";
} else {
resultDiv.className = "cin-result-box risk-high";
riskLevelTxt.innerHTML = "High Risk Profile";
riskDescTxt.innerHTML = "Significant risk factors detected (e.g., HR-HPV or abnormal Pap). It is highly recommended to schedule a clinical consultation and potentially a colposcopy.";
}
}